A large vertical rectangular tempera and gold painting on panel.The figure of Saint Anthony Abbot fills much of the center space of the panel. He sits on a throne holding a red-covered book with gilt trim in his right hand and a white staff in his left hand. He wears a very full and long dark robe with a lush grey collar, fastened at the neck, over a loose-fitting grey blouse. He has a high forehead and receding hairline; greyish hair is evident on the sides of his head. He has a mustache and a long, full beard that appears to be rolled into two spirals as they fall down onto his chest. The saint has a long, straight nose and dark eyes; his gaze is directly forward. Two angels stand just behind and to the sides of the saint, holding up a printed drape. They are highly similar in appearance, with light skin and blonde hair twisted into braids that frame their faces. They wear yellow robes over red gowns and a band of fabric over their shoulders that is decorated with Christian crosses. Two more angels stand at the bottom of the panel, also on either side. Both play medieval instruments as they gaze up at the saint. The angel to our left wears a blue gown with a red wrap; the angel to our right wears a red gown and a blue and yellow wrap. The panel is mounted in an ornate gilded frame. The sides of the frame are shaped as braided columns topped with flat-paneled columns. At the top of the columns, the frame forms an inverted V shape. Within this triangular section is a three-section cloverleaf within which is the figure of Christ. In his left hand, Christ holds a blue book with gilt trim; the fingers of his right hand form the symbol of the Trinity.